Rechallenge of everolimus for metastatic renal cell carcinoma after recovery from grade 3 interstitial lung disease : a case report
We report a case of the rechallenge of everolimus for metastatic renal cell carcinoma (RCC) after successful recovery from grade 3 interstitial lung disease (ILD). A 76-year-old man with metastatic RCC developed grade 3 ILD one month after the initiation of everolimus therapy (10 mg/day). ILD subsid...
Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 60(2014), 1 vom: 26. Jan., Seite 25-8 |
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1. Verfasser: | |
Weitere Verfasser: | , , , , , , , |
Format: | Aufsatz |
Sprache: | Japanese |
Veröffentlicht: |
2014
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Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
Schlagworte: | Case Reports Journal Article Antineoplastic Agents Enzyme Inhibitors Everolimus 9HW64Q8G6G Prednisolone 9PHQ9Y1OLM TOR Serine-Threonine Kinases EC 2.7.11.1 mehr... |
Zusammenfassung: | We report a case of the rechallenge of everolimus for metastatic renal cell carcinoma (RCC) after successful recovery from grade 3 interstitial lung disease (ILD). A 76-year-old man with metastatic RCC developed grade 3 ILD one month after the initiation of everolimus therapy (10 mg/day). ILD subsided in 4 months after the withdrawal of everolimus and treatment with corticosteroids. Half dose (5 mg/day) of everolimus was rechallenged for 9 months until another grade 3 ILD developed. Everolimus kept the disease under control for 13 months including the discontinuation period |
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Beschreibung: | Date Completed 13.05.2014 Date Revised 03.12.2021 published: Print Citation Status MEDLINE |
ISSN: | 0018-1994 |