Self-assembling properties of peptides derived from TDP-43 C-terminal fragment

Two highly fibrillogenic peptide sequences (MNFGAFSINP and EDLIIKGISV) were previously reported in the C-terminal fragment (CTF) of TDP-43 (220-414), a protein recently implicated in neuro-degenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-U...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 13 vom: 08. Apr., Seite 3845-56
1. Verfasser: Saini, Akash (VerfasserIn)
Weitere Verfasser: Chauhan, Virander S
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Benzothiazoles DNA-Binding Proteins Hydrogels Protein Aggregates Thiazoles thioflavin T 2390-54-7