Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 20 vom: 28. Mai, Seite 3253-7
1. Verfasser: Hashmi, Basma (VerfasserIn)
Weitere Verfasser: Zarzar, Lauren D, Mammoto, Tadanori, Mammoto, Akiko, Jiang, Amanda, Aizenberg, Joanna, Ingber, Donald E
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. biomaterials odontogenesis poly(N-isopropylacrylamide) scaffold engineering thermoresponsive Acrylic Resins mehr... Biocompatible Materials Bmp4 protein, mouse Bone Morphogenetic Protein 4 Hydrogels MSX1 Transcription Factor Msx1 protein, mouse Oligopeptides PAX9 Transcription Factor Paired Box Transcription Factors Pax9 protein, mouse poly-N-isopropylacrylamide 25189-55-3 glycyl-arginyl-glycyl-aspartyl-serine 96426-21-0
Beschreibung
Zusammenfassung:© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A biologically inspired thermoresponsive polymer has been developed that mechanically induces tooth differentiation in vitro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold. This normally occurs during the physiological mesenchymal condensation response that triggers tooth formation in the embryo
Beschreibung:Date Completed 11.05.2015
Date Revised 21.10.2021
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201304995