Six Kawasaki disease patients with acute coronary artery thrombosis

OBJECTIVE: To improve the awareness of acute coronary artery thrombosis in Kawasaki disease (KD)

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 51(2013), 12 vom: 03. Dez., Seite 925-9
1. Verfasser: Zhou, Shu-lai (VerfasserIn)
Weitere Verfasser: Luo, Jian-ping, Qi, Yan-qi, Liang, Yu-guang, Wang, Wei, Gong, Fang-qi
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't Anticoagulants Fibrinolytic Agents Immunoglobulins, Intravenous Aspirin R16CO5Y76E
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245 1 0 |a Six Kawasaki disease patients with acute coronary artery thrombosis 
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500 |a Date Revised 07.06.2016 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To improve the awareness of acute coronary artery thrombosis in Kawasaki disease (KD) 
520 |a METHOD: Six KD patients with acute coronary artery thrombosis (Jan. 2004 to Jan. 2013) were studied retrospectively. The basic information, clinical manifestations, laboratory data, echocardiography and electrocardiography (ECG), method and consequence of thrombolytic therapy were analyzed 
520 |a RESULT: The mean age of patients with coronary artery thrombosis (5 males and 1 female) was (17.2 ± 11.3) months.Five cases had thrombosis in left coronary artery (LCA), and four cases had thrombosis in aneurysm of left anterior descending artery (LAD). One case had thrombosis in both left and right coronary artery (RCA).One case died. Maximum thrombus was about 1.60 cm × 0.80 cm, locating in LAD. The diameter of LCA and RCA was (0.44 ± 0.07) cm and (0.45 ± 0.07) cm. Two patients showed abnormal ECG. Case 3 showed ST segment depression in lead V5. Case 6 showed myocardial infarction.In acute phase of KD, three patients received treatment with intravenous immunoglobin (IVIG), five patients were treated with aspirin.In sub-acute and convalescent phase of KD, all patients were treated with low-dose aspirin.Warfarin and dipyridamole were applied in 5 patients. All cases were treated with thrombolytic therapy using urokinase and/or heparin. After thrombolytic therapy, echocardiography showed thrombolysis in four cases and no change in one.One patient died of myocardial infarction 
520 |a CONCLUSION: Most of acute coronary thrombosis in KD occurred in LAD. KD patients with coronary artery thrombosis are at risk of sudden death due to myocardial infarction 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Anticoagulants  |2 NLM 
650 7 |a Fibrinolytic Agents  |2 NLM 
650 7 |a Immunoglobulins, Intravenous  |2 NLM 
650 7 |a Aspirin  |2 NLM 
650 7 |a R16CO5Y76E  |2 NLM 
700 1 |a Luo, Jian-ping  |e verfasserin  |4 aut 
700 1 |a Qi, Yan-qi  |e verfasserin  |4 aut 
700 1 |a Liang, Yu-guang  |e verfasserin  |4 aut 
700 1 |a Wang, Wei  |e verfasserin  |4 aut 
700 1 |a Gong, Fang-qi  |e verfasserin  |4 aut 
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