Bilateral cotton wool spots after use of an endothelin receptor antagonist

Copyright 2014, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 45(2014), 2 vom: 21. März, Seite 156-9
1. Verfasser: Khan, Mohammed A (VerfasserIn)
Weitere Verfasser: Pitcher, John D 3rd, Kawut, Steven M, Ho, Allen C
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Case Reports Journal Article Antihypertensive Agents Endothelin A Receptor Antagonists Phenylpropionates Pyridazines ambrisentan HW6NV07QEC
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520 |a Ambrisentan (Letairis; Gilead Sciences, Foster City, CA) is an endothelin receptor antagonist approved by the U.S. Food and Drug Administration for the treatment of pulmonary arterial hypertension. The authors describe the occurrence of bilateral cotton wool spots soon after initiation of ambrisentan treatment in a 29-year-old woman. Fluorescein angiography, optical coherence tomography, and fundus autofluorescence were performed. After discontinuation of ambrisentan, the cotton wool spots resolved without recurrence. To the authors' knowledge, this is the first report of retinopathy in the form of cotton wool spots associated with the use of an endothelin receptor antagonist 
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700 1 |a Ho, Allen C  |e verfasserin  |4 aut 
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