Alterations of SP-A, SP-D and KL-6 in serum and bronchoalveolar lavage fluid in children with Mycoplasma pneumoniae pneumonia

OBJECTIVE: To study the alterations and relationship of surfactant protein (SP)-A, SP-D and KL-6 in serum and bronchoalveolar lavage fluids (BALF) in children with Mycoplasma pneumoniae pneumonia (MPP)

Détails bibliographiques
Publié dans:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 51(2013), 10 vom: 09. Okt., Seite 779-82
Auteur principal: Shu, Lin-hua (Auteur)
Autres auteurs: Shang, Yun-xiao, Cai, Xu-xu, Zong, Zhi-hong, Meng, Xiao-na, Zhang, Han, Wang, Zhi-jia, Dai, Bing
Format: Article
Langue:Chinese
Publié: 2013
Accès à la collection:Zhonghua er ke za zhi = Chinese journal of pediatrics
Sujets:English Abstract Journal Article Research Support, Non-U.S. Gov't Biomarkers MUC1 protein, human Mucin-1 Pulmonary Surfactant-Associated Protein A Pulmonary Surfactant-Associated Protein D
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245 1 0 |a Alterations of SP-A, SP-D and KL-6 in serum and bronchoalveolar lavage fluid in children with Mycoplasma pneumoniae pneumonia 
264 1 |c 2013 
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500 |a Date Revised 07.06.2016 
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500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To study the alterations and relationship of surfactant protein (SP)-A, SP-D and KL-6 in serum and bronchoalveolar lavage fluids (BALF) in children with Mycoplasma pneumoniae pneumonia (MPP) 
520 |a METHOD: Self-control method was used for the study on SP-A, SP-D and KL-6 in serum, infected and non-infected BALFs in 32 MMP children with only one side of MPP 
520 |a RESULT: The contents of SP-A, SP-D and KL-6 in infected BALF were [mg/L;M (IQR) ]: 243 (90-468) , 187 (43-333) , 148 (47-426) ;104 (37-257) , 56 (25-131) , 35 (12-147) in non-infected BALF; 35 (25-69) , 33 (9-149) and 24 (15-62) in serum. The correlation coefficient of KL-6 between serum and infected BALF were -0.534 and -0.378 (P < 0.05) 
520 |a CONCLUSION: There were significant correlation between the alterations of SP-A, SP-D and KL-6 in serum and lung infection in children with CAP. KL-6 in serum may be more sensitive than SP-A and SP-D 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Mucin-1  |2 NLM 
650 7 |a Pulmonary Surfactant-Associated Protein A  |2 NLM 
650 7 |a Pulmonary Surfactant-Associated Protein D  |2 NLM 
700 1 |a Shang, Yun-xiao  |e verfasserin  |4 aut 
700 1 |a Cai, Xu-xu  |e verfasserin  |4 aut 
700 1 |a Zong, Zhi-hong  |e verfasserin  |4 aut 
700 1 |a Meng, Xiao-na  |e verfasserin  |4 aut 
700 1 |a Zhang, Han  |e verfasserin  |4 aut 
700 1 |a Wang, Zhi-jia  |e verfasserin  |4 aut 
700 1 |a Dai, Bing  |e verfasserin  |4 aut 
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