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01000naa a22002652 4500 |
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NLM234309067 |
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DE-627 |
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20231224101009.0 |
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tu |
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231224s2013 xx ||||| 00| ||chi c |
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|a pubmed24n0781.xml
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|a (DE-627)NLM234309067
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| 035 |
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|a (NLM)24406224
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| 040 |
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Cheng, Yun-gai
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Relationship between bronchoalveolar lavage mycoplasma load and clinical characteristics in children with Mycoplasma pneumoniae pneumonia
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| 264 |
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1 |
|c 2013
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 24.07.2014
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| 500 |
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|a Date Revised 07.06.2016
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|a published: Print
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| 500 |
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: Mycoplasma pneumoniae (MP) is an important pathogen for community-acquired pneumonia in children. MP infection was considered to be self-limited, but many severe refractory MP pneumonia cases have been reported in recent years. The reason for variation in severity of MP pneumonia remains unclear. MP virulence including drug-resistance and host immunologic function are important influencing factors. The present study aimed to clarify relationship between local MP load and severity of MP pneumonia
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| 520 |
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|a METHOD: MP DNA was quantitatively detected by fluorescent real-time PCR in bronchoalveolar lavage fluid (BALF) from 77 children with MP pneumonia. They were classified into groups of low MP load ( < 10(3)/ml, n = 14) , moderate MP load (10(3)-10(6)/ml, n = 22) and high MP load ( > 10(6)/ml, n = 41) . Clinical symptoms, main laboratory and imaging results of children among the three groups were compared
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| 520 |
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|a RESULT: When compared with low load group and moderate load group, high load group had longer fever duration (7 d, 10 d vs. 12 d) , longer time to normalization of temperature with macrolide administration (4 d, 8 d vs. 10 d) , more patients with high fever (50.0%, 68.2% vs. 87.8%) and longer duration of fever than 10 d (35.7%, 50.0% vs. 73.2%).Statistically significant difference existed in CRP among the three groups (1.0 mg/L, 11.5 mg/L, 34 mg/L). Large field of consolidation or atelectasis were found in 58.5% of high load patients, much higher than 22.7% in moderate load and 14.3% in low load patients. Bilateral or massive pleural effusion was not found in low load group, while in moderate load and high load group, they were 13.6% and 24.4%. However, no significant difference was found in symptoms and main laboratory and imaging results among different age groups in high load patients
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| 520 |
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|a CONCLUSION: There is a close relationship between MP load in BALF and clinical characteristics in children with MP pneumonia. Those with high MP load have a more severe process
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| 650 |
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4 |
|a English Abstract
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a DNA, Bacterial
|2 NLM
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| 700 |
1 |
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|a Li, Shu-xian
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Xue-jing
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chen, Ying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chen, Zhi-min
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 51(2013), 10 vom: 09. Okt., Seite 736-40
|w (DE-627)NLM136249191
|x 0578-1310
|7 nnns
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| 773 |
1 |
8 |
|g volume:51
|g year:2013
|g number:10
|g day:09
|g month:10
|g pages:736-40
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_11
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| 912 |
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|a GBV_ILN_20
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| 912 |
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|a GBV_ILN_22
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| 912 |
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|a GBV_ILN_24
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| 912 |
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|a GBV_ILN_31
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| 912 |
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|a GBV_ILN_39
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| 912 |
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|a GBV_ILN_40
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| 912 |
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|a GBV_ILN_50
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| 912 |
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|a GBV_ILN_61
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| 912 |
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|a GBV_ILN_65
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| 912 |
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|a GBV_ILN_69
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| 912 |
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|a GBV_ILN_70
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| 912 |
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|a GBV_ILN_72
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| 912 |
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|a GBV_ILN_120
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| 912 |
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|a GBV_ILN_130
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| 912 |
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|a GBV_ILN_227
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| 912 |
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|a GBV_ILN_244
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| 912 |
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|a GBV_ILN_285
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| 912 |
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|a GBV_ILN_294
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| 912 |
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|a GBV_ILN_350
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| 912 |
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|a GBV_ILN_665
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| 912 |
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|a GBV_ILN_813
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| 951 |
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|a AR
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| 952 |
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|d 51
|j 2013
|e 10
|b 09
|c 10
|h 736-40
|