Unveiling the membrane-binding properties of N-terminal and C-terminal regions of G protein-coupled receptor kinase 5 by combined optical spectroscopies

Unveiling the membrane-binding properties of N-terminal and C-terminal regions of G protein-coupled receptor kinase 5 by combined optical spectroscopies

G protein-coupled receptor kinase 5 (GRK5) is thought to associate with membranes in part via N- and C-terminal segments that are typically disordered in available high-resolution crystal structures. Herein we investigate the interactions of these regions with model cell membrane using combined sum...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 3 vom: 28. Jan., Seite 823-31
1. Verfasser: Ding, Bei (VerfasserIn)
Weitere Verfasser: Glukhova, Alisa, Sobczyk-Kojiro, Katarzyna, Mosberg, Henry I, Tesmer, John J G, Chen, Zhan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Lipid Bilayers Phosphatidylcholines G-Protein-Coupled Receptor Kinase 5 EC 2.7.11.16 GRK5 protein, human 1-palmitoyl-2-oleoylphosphatidylcholine TE895536Y5
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