Biophysical aspects of cyclodextrin interaction with paraoxon
Published 2013. This article is a U.S. Government work and is in the public domain in the USA.
| Veröffentlicht in: | Magnetic resonance in chemistry : MRC. - 1985. - 52(2014), 3 vom: 14. März, Seite 111-4 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2014
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| Zugriff auf das übergeordnete Werk: | Magnetic resonance in chemistry : MRC |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. 1H Benesi-Hildebrand plot Jobs plot NMR cyclodextrins molecular model organophosphate oxon paraoxon mehr... |
| Zusammenfassung: | Published 2013. This article is a U.S. Government work and is in the public domain in the USA. Cyclodextrins are torus-shaped polymers of glucose that can bind organophosphorous compounds such as nerve agents and pesticides. We demonstrate here that cyclodextrin can bind up to two paraoxon molecules with a K(av) of 6775 M(-1). Molecular modeling shows that the paraoxon appears to bind in polar opposite orientation and have an average binding energy of -89 Kcals/mol. Published 2013. This article is a U.S. Government work and is in the public domain in the USA |
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| Beschreibung: | Date Completed 07.10.2014 Date Revised 12.02.2014 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1097-458X |
| DOI: | 10.1002/mrc.4036 |