NMDA reduces Tau phosphorylation in rat hippocampal slices by targeting NR2A receptors, GSK3β, and PKC activities
The molecular mechanisms that regulate Tau phosphorylation are complex and currently incompletely understood. In the present study, pharmacological inhibitors were deployed to investigate potential processes by which the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors modulates Tau phosph...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Neural plasticity. - 1998. - 2013(2013) vom: 01., Seite 261593
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| 1. Verfasser: |
De Montigny, Audrée
(VerfasserIn) |
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| Weitere Verfasser: |
Elhiri, Ismaël,
Allyson, Julie,
Cyr, Michel,
Massicotte, Guy |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2013
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Antibodies, Blocking
Chromones
Epitopes
Excitatory Amino Acid Agonists
Morpholines
Protein Kinase Inhibitors
Receptors, N-Methyl-D-Aspartate
tau Proteins
mehr...
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
31M2U1DVID
N-Methylaspartate
6384-92-5
Glycogen Synthase Kinase 3 beta
EC 2.7.11.1
Gsk3b protein, rat
Protein Kinase C
EC 2.7.11.13
Glycogen Synthase Kinase 3
EC 2.7.11.26
Calcium
SY7Q814VUP
N-methyl D-aspartate receptor subtype 2A
VH92ICR8HX |
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