Quantitative PCR as a predictor of aligned ancient DNA read counts following targeted enrichment
Targeted DNA enrichment through hybridization capture (EHC) is rapidly replacing PCR as the method of choice for enrichment prior to genomic resequencing. This is especially true in the case of ancient DNA (aDNA) from long-dead organisms, where targets tend to be highly fragmented and outnumbered by...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | BioTechniques. - 1993. - 55(2013), 6 vom: 16. Dez., Seite 300-9
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1. Verfasser: |
Enk, Jacob
(VerfasserIn) |
Weitere Verfasser: |
Rouillard, Jean-Marie,
Poinar, Hendrik |
Format: | Online-Aufsatz
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Sprache: | English |
Veröffentlicht: |
2013
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Zugriff auf das übergeordnete Werk: | BioTechniques
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Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
ancient DNA
high-throughput sequencing
quantitative PCR
targeted enrichment
DNA, Mitochondrial
RNA, Ribosomal
RNA, ribosomal, 12S |