Quantitative PCR as a predictor of aligned ancient DNA read counts following targeted enrichment

Targeted DNA enrichment through hybridization capture (EHC) is rapidly replacing PCR as the method of choice for enrichment prior to genomic resequencing. This is especially true in the case of ancient DNA (aDNA) from long-dead organisms, where targets tend to be highly fragmented and outnumbered by...

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Veröffentlicht in:BioTechniques. - 1993. - 55(2013), 6 vom: 16. Dez., Seite 300-9
1. Verfasser: Enk, Jacob (VerfasserIn)
Weitere Verfasser: Rouillard, Jean-Marie, Poinar, Hendrik
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't ancient DNA high-throughput sequencing quantitative PCR targeted enrichment DNA, Mitochondrial RNA, Ribosomal RNA, ribosomal, 12S