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231224s2014 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201304107
|2 doi
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|a pubmed24n0779.xml
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|a eng
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1 |
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|a Guarrotxena, Nekane
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Antitags
|b SERS-encoded nanoparticle assemblies that enable single-spot multiplex protein detection
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|c 2014
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 25.11.2014
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Simultaneous detection of multiple proteins on a single spot can be efficiently achieved by using multiplexed surface-enhanced Raman spectroscopy (SERS)-encoded nanoparticle 'antitags' consisting of poly(ethylene glycol) (PEG)-protected silver dimers (and higher aggregates) and antibody-tagging entities. The effective SERS-based multivariate deconvolution approach guarantees an accurate and successful distinguishable identification of single and multiple proteins in complex samples. Their potential application in multiplexed SERS bioimaging technology can be easily envisaged
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Research Support, U.S. Gov't, Non-P.H.S.
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|a biosensors
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|a multiplex
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|a nanoparticles
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|a silver
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|a surface enhanced raman spectroscopy (SERS)
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|a 1,4-benzenedithiol
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|a Antibodies
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|a Biphenyl Compounds
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|a Proteins
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|a Silver Compounds
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|a Sulfhydryl Compounds
|2 NLM
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|a Polyethylene Glycols
|2 NLM
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|a 3WJQ0SDW1A
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|a Bazan, Guillermo C
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|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 26(2014), 12 vom: 26. März, Seite 1941-6
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