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|a pubmed24n0778.xml
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|a (DE-627)NLM233591907
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|a (NLM)24330983
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a chi
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100 |
1 |
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|a Leng, Hong-yao
|e verfasserin
|4 aut
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1 |
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|a Effects of different types and concentration of oral sweet solution on reducing neonatal pain during heel lance procedures
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|c 2013
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336 |
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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338 |
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|a Band
|b nc
|2 rdacarrier
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500 |
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|a Date Completed 04.09.2014
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|a Date Revised 07.06.2016
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To compare the effect of different types and concentrations of sweet solutions on neonatal pain during heel lance procedure
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|a METHOD: Totally 560 full term neonates (male 295, female 265) were randomized into 7 groups:placebo group (plain water), 10% glucose, 25% glucose, 50% glucose, 12% sucrose, 24% sucrose and 30% sucrose groups.In each group, 2 ml corresponding oral solutions were administered through a syringe by dripping into the neonate's mouth 2 minute before heel lance. The procedure process was recorded by videos, from which to collect heart rate, oxygen saturation and pain score 1 min before puncture, 3, 5 and 10 min after puncture
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|a RESULT: The average heart rate increase 3, 5 and 10 min after procedure in the 25% and 50% glucose groups, 12% and 24% and 30% sucrose groups was significantly lower than those in the placebo group (P < 0.01 or 0.05). The average heart rate increase 3 min after procedure in the sucrose group was lower than that in the glucose group (P < 0.01).Neonates who received 30% sucrose has a significantly lower average heart rate increase than those who received 12% and 24% sucrose 3 min after heel lance (both P < 0.05) . The average oxygen saturation decrease 3, 5, 10 min after procedure was significantly lower than those in the placebo group (P < 0.01). The average oxygen saturation decrease 3 min after procedure in the sucrose groups was significantly lower than that in the glucose groups (P < 0.01). The average pain score 3, 5, 10 min after procedure was significantly lower than those in the placebo group (P < 0.01). The average pain score 3 min after procedure in the sucrose groups was significantly lower than that in the glucose groups (P < 0.01)
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|a CONCLUSION: Oral administration of sweet solutions is an effective way to relieve neonatal pain on procedure, and sucrose has a better pain relief action than glucose, moreover, 30% sucrose provides better effect in control of heart rate increase 3 min after heel lance, but the best concentration of sucrose for pain relief needs further study
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|a English Abstract
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|a Journal Article
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|a Randomized Controlled Trial
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|a Research Support, Non-U.S. Gov't
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|a Analgesics
|2 NLM
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|a Sweetening Agents
|2 NLM
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|a Sucrose
|2 NLM
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7 |
|a 57-50-1
|2 NLM
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7 |
|a Glucose
|2 NLM
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7 |
|a IY9XDZ35W2
|2 NLM
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|a Oxygen
|2 NLM
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7 |
|a S88TT14065
|2 NLM
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700 |
1 |
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|a Zheng, Xian-lan
|e verfasserin
|4 aut
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700 |
1 |
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|a Yan, Li
|e verfasserin
|4 aut
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700 |
1 |
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|a Zhang, Xian-hong
|e verfasserin
|4 aut
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700 |
1 |
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|a He, Hua-yun
|e verfasserin
|4 aut
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700 |
1 |
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|a Xiang, Ming
|e verfasserin
|4 aut
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773 |
0 |
8 |
|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 51(2013), 9 vom: 18. Sept., Seite 654-8
|w (DE-627)NLM136249191
|x 0578-1310
|7 nnns
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773 |
1 |
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|g volume:51
|g year:2013
|g number:9
|g day:18
|g month:09
|g pages:654-8
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|a GBV_USEFLAG_A
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|a SYSFLAG_A
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|a AR
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|d 51
|j 2013
|e 9
|b 18
|c 09
|h 654-8
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