Effects of different types and concentration of oral sweet solution on reducing neonatal pain during heel lance procedures

OBJECTIVE: To compare the effect of different types and concentrations of sweet solutions on neonatal pain during heel lance procedure

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 51(2013), 9 vom: 18. Sept., Seite 654-8
1. Verfasser: Leng, Hong-yao (VerfasserIn)
Weitere Verfasser: Zheng, Xian-lan, Yan, Li, Zhang, Xian-hong, He, Hua-yun, Xiang, Ming
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Analgesics Sweetening Agents Sucrose 57-50-1 Glucose IY9XDZ35W2 mehr... Oxygen S88TT14065
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100 1 |a Leng, Hong-yao  |e verfasserin  |4 aut 
245 1 0 |a Effects of different types and concentration of oral sweet solution on reducing neonatal pain during heel lance procedures 
264 1 |c 2013 
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500 |a Date Completed 04.09.2014 
500 |a Date Revised 07.06.2016 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To compare the effect of different types and concentrations of sweet solutions on neonatal pain during heel lance procedure 
520 |a METHOD: Totally 560 full term neonates (male 295, female 265) were randomized into 7 groups:placebo group (plain water), 10% glucose, 25% glucose, 50% glucose, 12% sucrose, 24% sucrose and 30% sucrose groups.In each group, 2 ml corresponding oral solutions were administered through a syringe by dripping into the neonate's mouth 2 minute before heel lance. The procedure process was recorded by videos, from which to collect heart rate, oxygen saturation and pain score 1 min before puncture, 3, 5 and 10 min after puncture 
520 |a RESULT: The average heart rate increase 3, 5 and 10 min after procedure in the 25% and 50% glucose groups, 12% and 24% and 30% sucrose groups was significantly lower than those in the placebo group (P < 0.01 or 0.05). The average heart rate increase 3 min after procedure in the sucrose group was lower than that in the glucose group (P < 0.01).Neonates who received 30% sucrose has a significantly lower average heart rate increase than those who received 12% and 24% sucrose 3 min after heel lance (both P < 0.05) . The average oxygen saturation decrease 3, 5, 10 min after procedure was significantly lower than those in the placebo group (P < 0.01). The average oxygen saturation decrease 3 min after procedure in the sucrose groups was significantly lower than that in the glucose groups (P < 0.01). The average pain score 3, 5, 10 min after procedure was significantly lower than those in the placebo group (P < 0.01). The average pain score 3 min after procedure in the sucrose groups was significantly lower than that in the glucose groups (P < 0.01) 
520 |a CONCLUSION: Oral administration of sweet solutions is an effective way to relieve neonatal pain on procedure, and sucrose has a better pain relief action than glucose, moreover, 30% sucrose provides better effect in control of heart rate increase 3 min after heel lance, but the best concentration of sucrose for pain relief needs further study 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Randomized Controlled Trial 
650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Sweetening Agents  |2 NLM 
650 7 |a Sucrose  |2 NLM 
650 7 |a 57-50-1  |2 NLM 
650 7 |a Glucose  |2 NLM 
650 7 |a IY9XDZ35W2  |2 NLM 
650 7 |a Oxygen  |2 NLM 
650 7 |a S88TT14065  |2 NLM 
700 1 |a Zheng, Xian-lan  |e verfasserin  |4 aut 
700 1 |a Yan, Li  |e verfasserin  |4 aut 
700 1 |a Zhang, Xian-hong  |e verfasserin  |4 aut 
700 1 |a He, Hua-yun  |e verfasserin  |4 aut 
700 1 |a Xiang, Ming  |e verfasserin  |4 aut 
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