Panhypopituitarism caused by an intrasellar cystic mass in late-onset hypogonadism clinic

A 74-year-old man who was referred to our late onset hypogonadism clinic presented with sweating and loss of appetite. His aging males' symptoms (AMS) and international index of erectile function (IIEF-5) scores were 59 and 2, respectively. His hormonal examination revealed extremely low free t...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 59(2013), 10 vom: 15. Okt., Seite 683-6
1. Verfasser: Yamamoto, Yoshiyuki (VerfasserIn)
Weitere Verfasser: Takada, Shingo, Kinjo, Takanori, Nonomura, Daichi, Yoneda, Suguru, Nomura, Hironori, Tei, Norihide, Matsumiya, Kiyomi, Okusu, Takahiro
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports English Abstract Journal Article Adrenal Cortex Hormones Androgens Thyroid Hormones
Beschreibung
Zusammenfassung:A 74-year-old man who was referred to our late onset hypogonadism clinic presented with sweating and loss of appetite. His aging males' symptoms (AMS) and international index of erectile function (IIEF-5) scores were 59 and 2, respectively. His hormonal examination revealed extremely low free testosterone values. The patient was started on androgen replacement therapy, but his symptoms did not improve. Additional hormonal examinations revealed low values for other anterior pituitary hormones. Magnetic resonance imaging revealed an intrasellar cystic mass with suprasellar extension. We considered this mass caused hypothalamic hypopituitarism. A load test for anterior pituitary hormones revealed panhypogonadism. His symptoms improved after administration of adrenal and thyroid hormones and androgen. Five months after start of drug administration, his AMS score improved to 29, but IIEF-5 score showed little change. As a matter of course, not only androgen but all pituitary-related hormones are needed for hypopituitarism patients
Beschreibung:Date Completed 16.01.2014
Date Revised 22.11.2013
published: Print
Citation Status MEDLINE
ISSN:0018-1994