Combination anti-VEGF and corticosteroid therapy for idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome

Copyright 2013, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 44(2013), 6 vom: 01. Nov., Seite 599-602
1. Verfasser: Sawhney, Gagan K (VerfasserIn)
Weitere Verfasser: Payne, John F, Ray, Robin, Mehta, Sonia, Bergstrom, Chris S, Yeh, Steven
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Case Reports Journal Article Research Support, Non-U.S. Gov't Adrenal Cortex Hormones Angiogenesis Inhibitors Antibodies, Monoclonal, Humanized Bevacizumab 2S9ZZM9Q9V
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520 |a Vision loss associated with the idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome most commonly occurs from macular edema or complications related to neovascularization. The authors present a case of advanced IRVAN associated with a massive exudative response characterized by peripheral retinal telangiectasias, exudative retinal detachment, and macular edema with lipid maculopathy. The patient was managed successfully with visual acuity from hand motion to 20/150 using a combination of local corticosteroids, intravitreal bevacizumab, panretinal photocoagulation, and eventually pars plana vitrectomy for progressive vitreomacular traction. VEGF- and non-VEGF-mediated mechanisms appear to be involved in the pathogenesis of IRVAN given the efficacy of combination therapy. [ophthalmic surg lasers imaging retina. 2013;44:599-602.] 
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700 1 |a Bergstrom, Chris S  |e verfasserin  |4 aut 
700 1 |a Yeh, Steven  |e verfasserin  |4 aut 
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