Triggered sorting and co-assembly of genetically engineered protein microdomains in the cytoplasm

Triggered sorting and co-assembly of genetically engineered protein microdomains in the cytoplasm

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 3 vom: 22. Jan., Seite 449-54
1. Verfasser: Shi, Pu (VerfasserIn)
Weitere Verfasser: Lin, Yi-An, Pastuszka, Martha, Cui, Honggang, Mackay, J Andrew
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't confocal microscopy elastin-like polypeptides intracellular sorting macromolecular assembly protein polymer Luminescent Proteins Peptides mehr... fluorescent protein 583 Green Fluorescent Proteins 147336-22-9
Beschreibung
Zusammenfassung:© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Elastin-like polypeptides (ELPs) are genetically encoded protein polymers that reversibly phase separate in response to stimuli. They respond sharply to small shifts in temperature and form dense microdomains in the living eukaryotic cytosol. For the first time, this communication illustrates how to tune the ELP sequence and architecture for either co-assembly or sorting of distinct proteins into microdomains within a living cell
Beschreibung:Date Completed 24.10.2014
Date Revised 21.03.2024
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201303356