Spatiotemporal drug release visualized through a drug delivery system with tunable aggregation-induced emission

Spatiotemporal drug release visualized through a drug delivery system with tunable aggregation-induced emission

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 5 vom: 07. Feb., Seite 712-7
1. Verfasser: Xue, Xiangdong (VerfasserIn)
Weitere Verfasser: Zhao, Yuanyuan, Dai, Luru, Zhang, Xu, Hao, Xiaohong, Zhang, Chunqiu, Huo, Shuaidong, Liu, Juan, Liu, Chang, Kumar, Anil, Chen, Wei-Qiang, Zou, Guozhang, Liang, Xing-Jie
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't aggregation-induced emission drug delivery system nanoaggregation self-indicating nanoparticles spatiotemporal drug release Drug Carriers Doxorubicin 80168379AG
Beschreibung
Zusammenfassung:© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Tetraphenylethene and doxorubicin are assembled into a self-indicating drug delivery system (TD NPs). TD NPs are decomposed into DOX and TPE NPs in lysosome. Since TD NPs, TPE NPs and DOX are all fluorescent, the detachment of DOX from TPE NPs is accompanied by fluorescence changing. By observing the fluorescence changes, the spatiotemporal drug release is visualized
Beschreibung:Date Completed 29.09.2014
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201302365