Biophysically defined and cytocompatible covalently adaptable networks as viscoelastic 3D cell culture systems

Biophysically defined and cytocompatible covalently adaptable networks as viscoelastic 3D cell culture systems

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 6 vom: 12. Feb., Seite 865-72
1. Verfasser: McKinnon, Daniel D (VerfasserIn)
Weitere Verfasser: Domaille, Dylan W, Cha, Jennifer N, Anseth, Kristi S
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Validation Study dynamic materials hydrogels polymeric materials self-healing materials supramolecular chemistry mehr... Aldehydes Benzaldehydes Biocompatible Materials Hydrazones Hydrogels Viscoelastic Substances Polyethylene Glycols 3WJQ0SDW1A 4-nitrobenzaldehyde 555-16-8 butyraldehyde H21352682A benzaldehyde TA269SD04T
Beschreibung
Zusammenfassung:© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Presented here is a cytocompatible covalently adaptable hydrogel uniquely capable of mimicking the complex biophysical properties of native tissue and enabling natural cell functions without matrix degradation. Demonstrated is both the ability to control elastic modulus and stress relaxation time constants by more than an order of magnitude while predicting these values based on fundamental theoretical understanding and the simulation of muscle tissue and the encapsulation of myoblasts
Beschreibung:Date Completed 10.10.2014
Date Revised 11.11.2023
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201303680