Using NMR chemical shift imaging to monitor swelling and molecular transport in drug-loaded tablets of hydrophobically modified poly(acrylic acid) : methodology and effects of polymer (in)solubility

A new technique has been developed using NMR chemical shift imaging (CSI) to monitor water penetration and molecular transport in initially dry polymer tablets that also contain small low-molecular weight compounds to be released from the tablets. Concentration profiles of components contained in th...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 45 vom: 12. Nov., Seite 13898-908
1. Verfasser: Knöös, Patrik (VerfasserIn)
Weitere Verfasser: Topgaard, Daniel, Wahlgren, Marie, Ulvenlund, Stefan, Piculell, Lennart
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Acrylic Resins Drug Carriers Pharmaceutical Preparations Tablets Griseofulvin 32HRV3E3D5 carbopol 940 4Q93RCW27E mehr... Deuterium Oxide J65BV539M3