Using NMR chemical shift imaging to monitor swelling and molecular transport in drug-loaded tablets of hydrophobically modified poly(acrylic acid) : methodology and effects of polymer (in)solubility
A new technique has been developed using NMR chemical shift imaging (CSI) to monitor water penetration and molecular transport in initially dry polymer tablets that also contain small low-molecular weight compounds to be released from the tablets. Concentration profiles of components contained in th...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 45 vom: 12. Nov., Seite 13898-908
|
1. Verfasser: |
Knöös, Patrik
(VerfasserIn) |
Weitere Verfasser: |
Topgaard, Daniel,
Wahlgren, Marie,
Ulvenlund, Stefan,
Piculell, Lennart |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2013
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Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Acrylic Resins
Drug Carriers
Pharmaceutical Preparations
Tablets
Griseofulvin
32HRV3E3D5
carbopol 940
4Q93RCW27E
mehr...
Deuterium Oxide
J65BV539M3 |