Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled m...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 40 vom: 08. Okt., Seite 12352-7
1. Verfasser: Abbaspourrad, Alireza (VerfasserIn)
Weitere Verfasser: Duncanson, Wynter J, Lebedeva, Natalia, Kim, Shin-Hyun, Zhushma, Aleksandr P, Datta, Sujit S, Dayton, Paul A, Sheiko, Sergei S, Rubinstein, Michael, Weitz, David A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Capsules
Beschreibung
Zusammenfassung:We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs
Beschreibung:Date Completed 08.05.2014
Date Revised 08.10.2013
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la402598p