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231224s2013 xx |||||o 00| ||eng c |
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|a 10.1021/la402708u
|2 doi
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|a eng
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|a Gerelli, Yuri
|e verfasserin
|4 aut
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|a Lipid exchange and flip-flop in solid supported bilayers
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|c 2013
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|a Text
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 06.05.2014
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|a Date Revised 15.10.2013
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Inter- and intrabilayer transfer of phospholipid molecules was investigated by neutron reflectometry. The structure of solid supported lipid bilayers exposed to a solution of isotopically labeled vesicles was monitored as a function of temperature, time, and vesicle concentration. Lipid interbilayer exchange was shown to be the time limiting process, while lipid intrabilayer movement, the so-called flip-flop, was too fast to be visualized within the experimental acquisition time. The exchange process was characterized by an Arrhenius-like behavior and the activation energy of the process was concentration-independent. The results are discussed and compared extensively with the literature available on the topic
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Lipid Bilayers
|2 NLM
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|a Phospholipids
|2 NLM
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|a Porcar, Lionel
|e verfasserin
|4 aut
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|a Lombardi, Lucia
|e verfasserin
|4 aut
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1 |
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|a Fragneto, Giovanna
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 29(2013), 41 vom: 15. Okt., Seite 12762-9
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|x 1520-5827
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|g volume:29
|g year:2013
|g number:41
|g day:15
|g month:10
|g pages:12762-9
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