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231224s2013 xx |||||o 00| ||eng c |
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7 |
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|a 10.3928/23258160-20130909-06
|2 doi
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|a pubmed24n0769.xml
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|a (DE-627)NLM230953182
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|a (NLM)24044707
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Olson, Joanna M
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Association between systemic anticoagulation and rate of intraocular hemorrhage following intravitreal anti-VEGF therapy for age-related macular degeneration
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|c 2013
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 17.03.2014
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|a Date Revised 22.10.2015
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright 2013, SLACK Incorporated.
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|a BACKGROUND AND OBJECTIVE: To investigate the association between systemic anticoagulant medication usage at the time of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection with post-injection intraocular hemorrhage among patients with age-related macular degeneration (AMD)
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| 520 |
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|a PATIENTS AND METHODS: Retrospective, consecutive case series of all patients treated with anti-VEGF injection for neovascular AMD at the Penn State Hershey Eye Center between 2004 and 2010: 1,710 anti-VEGF injections performed in 228 eyes of 191 patients. Each injection was analyzed according to whether the patient was taking systemic anticoagulant medication at the time of injection
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|a RESULTS: Intraocular hemorrhage occurred after intravitreal anti-VEGF injection in four eyes (0.25%). Vitreous hemorrhage occurred in three patients taking systemic anticoagulation. Subretinal hemorrhage occurred in one patient not on anticoagulant therapy. In a bivariate analysis, the odds of intraocular hemorrhage are 1.9 times higher for injections performed in patients on systemic anticoagulation versus those not on systemic anticoagulation; this difference is not statistically significant
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| 520 |
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|a CONCLUSION: The rate of intraocular hemorrhage after intravitreal injection of anti-VEGF therapy among patients with AMD is low, and there is no significant difference between patients taking systemic anticoagulant medications at the time of injection and patients not on anticoagulation
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|a Journal Article
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|a Angiogenesis Inhibitors
|2 NLM
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| 650 |
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|a Anticoagulants
|2 NLM
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| 650 |
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7 |
|a Vascular Endothelial Growth Factor A
|2 NLM
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| 700 |
1 |
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|a Scott, Ingrid U
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kerchner, Denise L
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kunselman, Allen R
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 44(2013), 5 vom: 17. Sept., Seite 455-9
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnns
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| 773 |
1 |
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|g volume:44
|g year:2013
|g number:5
|g day:17
|g month:09
|g pages:455-9
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|u http://dx.doi.org/10.3928/23258160-20130909-06
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