Esterification Catalysis by Pyridinium p-Toluenesulfonate Revisited-Modification with a Lipid Chain for Improved Activities and Selectivities

The lipid analogues of pyridinium p-toluenesulfonate (PPTS) were examined for catalyzing the condensation of an equimolar mixture of carboxylic acids and alcohols under mild conditions without removal of water. Although PPTS is a poor catalyst, the introduction of a lipid chain and nitro group signi...

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Détails bibliographiques
Publié dans:Synthetic communications. - 1998. - 43(2013), 21 vom: 01. Jan., Seite 2906-2912
Auteur principal: Wang, Wei (Auteur)
Autres auteurs: Liu, Huimin, Xu, Shaoyi, Gao, Yong
Format: Article
Langue:English
Publié: 2013
Accès à la collection:Synthetic communications
Sujets:Journal Article
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520 |a The lipid analogues of pyridinium p-toluenesulfonate (PPTS) were examined for catalyzing the condensation of an equimolar mixture of carboxylic acids and alcohols under mild conditions without removal of water. Although PPTS is a poor catalyst, the introduction of a lipid chain and nitro group significantly improved the activity of PPTS and led to selectivity at suppressing elimination side reactions of alcohols. 2-Oleamido-5-nitro-pyridinium p-toluenesulfonate (6) is a lead catalyst that promoted various esterification reactions with yields up to 99% 
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700 1 |a Gao, Yong  |e verfasserin  |4 aut 
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