Membrane-mediated neuroprotection by curcumin from amyloid-β-peptide-induced toxicity

Amyloid-β peptide (Aβ)-membrane interactions have been implicated in the formation of toxic oligomers that permeabilize membranes, allowing an influx of calcium ions and triggering cell death in the pathogenesis of Alzheimer's disease (AD). Curcumin, a small dietary polyphenolic molecule, has b...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 37 vom: 17. Sept., Seite 11713-23
1. Verfasser: Thapa, Arjun (VerfasserIn)
Weitere Verfasser: Vernon, Briana C, De la Peña, Karen, Soliz, Gregory, Moreno, Hector A, López, Gabriel P, Chi, Eva Y
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Amyloid beta-Peptides Neuroprotective Agents Curcumin IT942ZTH98