ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

The TOR (target of rapamycin) protein, a large phosphatidylinositol 3-kinase-like protein kinase (PIKK) that is conserved in eukaryotes and is a central regulator of growth and metabolism. The analysis of function of TOR in plant growth and development has been limited by the fact that plants are ve...

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Veröffentlicht in:	Journal of experimental botany. - 1985. - 64(2013), 14 vom: 20. Nov., Seite 4361-74
1. Verfasser:	Montané, Marie-Hélène (VerfasserIn)
Weitere Verfasser:	Menand, Benoît
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2013
Zugriff auf das übergeordnete Werk:	Journal of experimental botany
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't ATP-competitive mTOR kinase inhibitors Arabidopsis Lotus Nicotiana cell size differentiation meristem millet mehr... rice root growth root hairs target of rapamycin. 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo(h)(1,6)naphthyridin-2(1H)-one Arabidopsis Proteins Morpholines Naphthyridines Phenylurea Compounds Protein Kinase Inhibitors Pyrazoles WYE 125132 Adenosine Triphosphate 8L70Q75FXE (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol 970JJ37FPW TOR Serine-Threonine Kinases EC 2.7.11.1 Sirolimus W36ZG6FT64