Allergic reaction to abciximab with atypical manifestations

Abciximab (ReoPro, Eli Lilly and Company, Indianapolis, Indiana) is an intravenous agent that had been approved for treatment of acute coronary syndrome undergoing coronary interventions. It is a chimeric monoclonal antibody fragment that binds to the glycoprotein IIb/IIIa receptor with a potential...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 23(2011), 2 vom: 20. Apr., Seite 97-9
1. Verfasser: Al-Moghairi, Abdulrahman M (VerfasserIn)
Weitere Verfasser: Abdullah, Moheeb A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2011
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article Abciximab Allergic reaction Coronary intervention Glycoprotein IIb/IIIa inhibitor
Beschreibung
Zusammenfassung:Abciximab (ReoPro, Eli Lilly and Company, Indianapolis, Indiana) is an intravenous agent that had been approved for treatment of acute coronary syndrome undergoing coronary interventions. It is a chimeric monoclonal antibody fragment that binds to the glycoprotein IIb/IIIa receptor with a potential for the development of an immune response to variable portions within the antigen binding site following its administration. We describe a 58-year-old man who developed sudden headache, short of breath, choking and restlessness after receiving Abciximab for coronary intervention. Discontinuation of abciximab and administration of intravenous fluids, steroid and antihistamines led to improvement of his symptoms gradually
Beschreibung:Date Completed 20.08.2013
Date Revised 21.10.2021
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1016-7315
DOI:10.1016/j.jsha.2010.12.002