Mechanical ventilation strategy following Glenn and Fontan surgeries : On going challenge!

The Glenn and Fontan operations put the pulmonary and systemic circulations in series. It has been shown that positive pressure ventilation (PPV) decreases pulmonary blood flow (PBF) and cardiac output (CO), and negative pressure ventilation (NPV) significantly improves PBF and CO. If early extubati...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 21(2009), 3 vom: 20. Juli, Seite 153-7
1. Verfasser: Al-Eyadhy, Ayman (VerfasserIn)
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article CO, cardiac output CO2, carbon dioxide IVC, inferior Vena Cava NPV, negative pressure ventilation PBF, pulmonary blood flow PDA, patent ductus arteriosus PEEP, positive end-expiratory pressure PPV, positive pressure ventilation PVR, pulmonary vascular resistance mehr... SaO2, arterial saturation TPG, transpulmonary gradient iNO, inhaled nitric oxide
Beschreibung
Zusammenfassung:The Glenn and Fontan operations put the pulmonary and systemic circulations in series. It has been shown that positive pressure ventilation (PPV) decreases pulmonary blood flow (PBF) and cardiac output (CO), and negative pressure ventilation (NPV) significantly improves PBF and CO. If early extubation is not achievable, the postoperative ventilator management strategy should aim at promoting PBF and CO by lowering pulmonary vascular resistance (PVR) and intrathoracic pressure. Multiple ventilator strategies have been evaluated to optimize this physiology, including high frequency ventilation, hyperventilation post Glenn, hypoventilation post Glenn with buffered pH, and the use of inhaled nitric oxide as an adjunct therapy for mechanical ventilation. In this review, the results of these studies will be reviewed and discussed
Beschreibung:Date Completed 20.08.2013
Date Revised 21.10.2021
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1016-7315
DOI:10.1016/j.jsha.2009.06.005