A selective artificial enzyme inhibitor based on nanoparticle-enzyme interactions and molecular imprinting

A selective artificial enzyme inhibitor based on nanoparticle-enzyme interactions and molecular imprinting

© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 25(2013), 41 vom: 06. Nov., Seite 5922-7
1. Verfasser: Zheng, Cheng (VerfasserIn)
Weitere Verfasser: Zhang, Xiao-Long, Liu, Wei, Liu, Bo, Yang, Huang-Hao, Lin, Zi-An, Chen, Guo-Nan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't enzyme inhibitor molecular imprinted polymers molecular recognition nanoparticles Nanotubes, Carbon Polymers Protease Inhibitors Chymotrypsin mehr... EC 3.4.21.1 alpha-chymotrypsin
Beschreibung
Zusammenfassung:© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A novel and general strategy is developed to design selective artificial enzyme inhibitor based on nanoparticleenzyme inter actions and molecular imprinting. Due to the creation of specific binding cavities, the resulting artificial inhibitor has high inhibition efficiency for the target enzyme, and shows great target-selectivity over other enzymes of similar function and proteins of compaable mole cular weight
Beschreibung:Date Completed 06.10.2014
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201302064