Impacts of chloramine-T treatment on antioxidant enzyme activities and genotoxicity in rainbow trout, Oncorhynchus mykiss (Walbaum)

© 2013 John Wiley & Sons Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Journal of fish diseases. - 1998. - 37(2014), 5 vom: 03. Mai, Seite 431-41
1. Verfasser: Boran, H (VerfasserIn)
Weitere Verfasser: Altinok, I
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Journal of fish diseases
Schlagworte:Journal Article Research Support, Non-U.S. Gov't chloramine-T comet assay enzyme activity genotoxicity rainbow trout Anti-Bacterial Agents Chloramines Fish Proteins mehr... Tosyl Compounds Oxidoreductases EC 1.-
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520 |a Juvenile rainbow trout Oncorhynchus mykiss (Walbaum) were exposed to therapeutic, and higher concentrations of chloramine-T (Cl-T) to assess the effects of this chemical on the antioxidant enzyme system and genetic structure. Red blood cells acetylcholinesterase, ∆-aminolevulinic acid dehydratase, paraoxonase and liver glutathione S-transferase activity were increased at 10 and 20 mg L(-1) Cl-T-exposed fish, while they were decreased at 30 mg L(-1) Cl-T-exposed fish. On the other hand, liver catalase activity and liver protein levels increased at 10 mg L(-1) and decreased at 20 and 30 mg L(-1) concentrations of Cl-T. Liver super-oxide dismutase activity decreased at 10 mg L(-1) and 20 mg L(-1) Cl-T and increased at 30 mg L(-1) of Cl-T. Compared to control, comet assay indicated that Cl-T did not cause significant DNA damage to red blood cells of the fish. Results indicate that 10 or 20 mg L(-1) Cl-T can be safely used to prevent or treat external parasitic and bacterial infection of rainbow trout 
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650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a chloramine-T 
650 4 |a comet assay 
650 4 |a enzyme activity 
650 4 |a genotoxicity 
650 4 |a rainbow trout 
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650 7 |a Chloramines  |2 NLM 
650 7 |a Fish Proteins  |2 NLM 
650 7 |a Tosyl Compounds  |2 NLM 
650 7 |a chloramine-T  |2 NLM 
650 7 |a Oxidoreductases  |2 NLM 
650 7 |a EC 1.-  |2 NLM 
700 1 |a Altinok, I  |e verfasserin  |4 aut 
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