Effects of low-level hexabromocyclododecane (HBCD) exposure on cardiac development in zebrafish embryos

Hexabromocyclododecane (HBCD) is one of the most widely used brominated flame retardants. In the present study, zebrafish embryos were exposed to HBCD at the low concentrations of 0, 2, 20 and 200 nM. The results showed HBCD exposure resulted in an increase in heart rate and cardiac arrhythmia after...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 22(2013), 8 vom: 21. Okt., Seite 1200-7
1. Verfasser: Wu, Meifang (VerfasserIn)
Weitere Verfasser: Zuo, Zhenghong, Li, Bowen, Huang, Lixing, Chen, Meng, Wang, Chonggang
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Flame Retardants Homeobox Protein Nkx-2.5 Hydrocarbons, Brominated Nkx2.5 protein, zebrafish RNA, Messenger Ryanodine Receptor Calcium Release Channel T-Box Domain Proteins T-box transcription factor 5 mehr... Transcription Factors Troponin T Zebrafish Proteins myh6 protein, zebrafish tnnt2a protein, zebrafish hexabromocyclododecane 5I9835JO3M Caspase 3 EC 3.4.22.- Sarcoplasmic Reticulum Calcium-Transporting ATPases EC 3.6.3.8 Myosin Heavy Chains EC 3.6.4.1