Rational design of multifunctional upconversion nanocrystals/polymer nanocomposites for cisplatin (IV) delivery and biomedical imaging

Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 25(2013), 35 vom: 20. Sept., Seite 4898-905
1. Verfasser: Ma, Ping'an (VerfasserIn)
Weitere Verfasser: Xiao, Haihua, Li, Xiaoxue, Li, Chunxia, Dai, Yunlu, Cheng, Ziyong, Jing, Xiabin, Lin, Jun
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't biomedical imaging cisplatin drug delivery self-assembly upconversion fluorescent Antineoplastic Agents Fluorescent Dyes Polymers mehr... Cisplatin Q20Q21Q62J
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520 |a By combining upconversion nanoparticles with the cisplatin (IV) prodrug we have demonstrated that a stable and multifunctional drug delivery system can be designed that will both reduce the drawbacks of cisplatin and give insight in to its in vitro/in vivo imaging. The up/down-conversion fluorescence are detectable and show obvious co-localization, demonstrating that the nanoparticles are rather stable inside cells and retain the UCNPs and block copolymer 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a biomedical imaging 
650 4 |a cisplatin 
650 4 |a drug delivery 
650 4 |a self-assembly 
650 4 |a upconversion fluorescent 
650 7 |a Antineoplastic Agents  |2 NLM 
650 7 |a Fluorescent Dyes  |2 NLM 
650 7 |a Polymers  |2 NLM 
650 7 |a Cisplatin  |2 NLM 
650 7 |a Q20Q21Q62J  |2 NLM 
700 1 |a Xiao, Haihua  |e verfasserin  |4 aut 
700 1 |a Li, Xiaoxue  |e verfasserin  |4 aut 
700 1 |a Li, Chunxia  |e verfasserin  |4 aut 
700 1 |a Dai, Yunlu  |e verfasserin  |4 aut 
700 1 |a Cheng, Ziyong  |e verfasserin  |4 aut 
700 1 |a Jing, Xiabin  |e verfasserin  |4 aut 
700 1 |a Lin, Jun  |e verfasserin  |4 aut 
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