Modifications of microvascular EC surface modulate phototoxicity of a porphycene anti-ICAM-1 immunoconjugate; therapeutic implications
Inflammation and shear stress can upregulate expression of cellular adhesion molecules in endothelial cells (EC). The modified EC surface becomes a mediating interface between the circulating blood elements and the endothelium, and grants opportunity for immunotherapy. In photodynamic therapy (PDT),...
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| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 31 vom: 06. Aug., Seite 9734-43
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| 1. Verfasser: |
Rosàs, Elisabet
(VerfasserIn) |
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| Weitere Verfasser: |
Santomá, Pablo,
Duran-Frigola, Miquel,
Hernandez, Bryan,
Llinàs, Maria C,
Ruiz-González, Rubén,
Nonell, Santi,
Sánchez-García, David,
Edelman, Elazer R,
Balcells, Mercedes |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2013
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Immunoconjugates
Photosensitizing Agents
Porphyrins
porphycene
100572-96-1
Intercellular Adhesion Molecule-1
126547-89-5 |
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