Multiwalled carbon nanotubes and NaYF4:Yb3+/Er3+ nanoparticle-doped bilayer hydrogel for concurrent NIR-triggered drug release and up-conversion luminescence tagging

Bilayer thermosensitive P(NIPAm-co-AAm) hydrogel discs were prepared by a facile UV light initiation process from N-isopropylacrylamide (NIPAm) and acrylamide (AAm) monomers' cross-linking copolymerization. Poly(ethylene glycol) (PEG) as a pore-forming agent was added in order to form a porous...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 30 vom: 30. Juli, Seite 9573-80
1. Verfasser: Cheng, Ziyong (VerfasserIn)
Weitere Verfasser: Chai, Ruitao, Ma, Pingan, Dai, Yunlu, Kang, Xiaojiao, Lian, Hongzhou, Hou, Zhiyao, Li, Chunxia, Lin, Jun
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Acrylic Resins Biocompatible Materials Drug Carriers Hydrogels Luminescent Agents Nanotubes, Carbon poly(N-isopropylacrylamide-co-acrylamide) sodium yttriumtetrafluoride mehr... Yttrium 58784XQC3Y Erbium 77B218D3YE Ytterbium MNQ4O4WSI1 Fluorides Q80VPU408O
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100 1 |a Cheng, Ziyong  |e verfasserin  |4 aut 
245 1 0 |a Multiwalled carbon nanotubes and NaYF4:Yb3+/Er3+ nanoparticle-doped bilayer hydrogel for concurrent NIR-triggered drug release and up-conversion luminescence tagging 
264 1 |c 2013 
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500 |a Date Revised 31.07.2013 
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500 |a Citation Status MEDLINE 
520 |a Bilayer thermosensitive P(NIPAm-co-AAm) hydrogel discs were prepared by a facile UV light initiation process from N-isopropylacrylamide (NIPAm) and acrylamide (AAm) monomers' cross-linking copolymerization. Poly(ethylene glycol) (PEG) as a pore-forming agent was added in order to form a porous structure and improve the water content in the hydrogel. Functional materials of NaYF4:Yb(3+)/Er(3+) nanoparticles and multiwalled carbon nanotubes (MWCNTs) were incorporated into different layers of the P(NIPAm-co-AAm) hydrogel for the purpose of up-conversion luminescence labeling and the NIR light antenna effect, respectively. Significantly improved drug release from composite hydrogels was achieved in response to 980 nm NIR light irradiation by using lysozyme as a macromolecular drug. The multifunctional hydrogel reported here provides a platform for simultaneous NIR luminescence labeling and NIR-driven drug release 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Acrylic Resins  |2 NLM 
650 7 |a Biocompatible Materials  |2 NLM 
650 7 |a Drug Carriers  |2 NLM 
650 7 |a Hydrogels  |2 NLM 
650 7 |a Luminescent Agents  |2 NLM 
650 7 |a Nanotubes, Carbon  |2 NLM 
650 7 |a poly(N-isopropylacrylamide-co-acrylamide)  |2 NLM 
650 7 |a sodium yttriumtetrafluoride  |2 NLM 
650 7 |a Yttrium  |2 NLM 
650 7 |a 58784XQC3Y  |2 NLM 
650 7 |a Erbium  |2 NLM 
650 7 |a 77B218D3YE  |2 NLM 
650 7 |a Ytterbium  |2 NLM 
650 7 |a MNQ4O4WSI1  |2 NLM 
650 7 |a Fluorides  |2 NLM 
650 7 |a Q80VPU408O  |2 NLM 
700 1 |a Chai, Ruitao  |e verfasserin  |4 aut 
700 1 |a Ma, Pingan  |e verfasserin  |4 aut 
700 1 |a Dai, Yunlu  |e verfasserin  |4 aut 
700 1 |a Kang, Xiaojiao  |e verfasserin  |4 aut 
700 1 |a Lian, Hongzhou  |e verfasserin  |4 aut 
700 1 |a Hou, Zhiyao  |e verfasserin  |4 aut 
700 1 |a Li, Chunxia  |e verfasserin  |4 aut 
700 1 |a Lin, Jun  |e verfasserin  |4 aut 
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773 1 8 |g volume:29  |g year:2013  |g number:30  |g day:30  |g month:07  |g pages:9573-80 
856 4 0 |u http://dx.doi.org/10.1021/la402036p  |3 Volltext 
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