Prevention versus intervention of type 1 diabetes

Copyright © 2013 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 149(2013), 3 vom: 23. Dez., Seite 332-8
1. Verfasser: Brooks-Worrell, Barbara (VerfasserIn)
Weitere Verfasser: Palmer, Jerry P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Review Intervention Islet autoimmunity Prediction Prevention Type 1 diabetes Type 2 diabetes Antibodies, Monoclonal, Humanized CD3 Complex mehr... Hypoglycemic Agents Immunoconjugates Immunoglobulin G Insulin Receptors, Tumor Necrosis Factor Abatacept 7D0YB67S97 Glutamate Decarboxylase EC 4.1.1.15 Etanercept OP401G7OJC teplizumab S4M959U2IJ
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520 |a Type 1 diabetes (T1D) is a cell-mediated autoimmune disease. New cases of T1D are on the increase and exogenous insulin therapy is the only intervention regularly initiated for T1D patients. Though tremendous strides have been made in prediction of T1D, prevention and intervention strategies have not experienced the same success. In this review, we will discuss some possible reasons why new intervention therapies for T1D have not been implemented into the mainstream treatment regimen for T1D patients. We will also discuss potential caveats for why prevention and intervention trials in T1D may not have experienced the same success as prediction trials 
650 4 |a Journal Article 
650 4 |a Review 
650 4 |a Intervention 
650 4 |a Islet autoimmunity 
650 4 |a Prediction 
650 4 |a Prevention 
650 4 |a Type 1 diabetes 
650 4 |a Type 2 diabetes 
650 7 |a Antibodies, Monoclonal, Humanized  |2 NLM 
650 7 |a CD3 Complex  |2 NLM 
650 7 |a Hypoglycemic Agents  |2 NLM 
650 7 |a Immunoconjugates  |2 NLM 
650 7 |a Immunoglobulin G  |2 NLM 
650 7 |a Insulin  |2 NLM 
650 7 |a Receptors, Tumor Necrosis Factor  |2 NLM 
650 7 |a Abatacept  |2 NLM 
650 7 |a 7D0YB67S97  |2 NLM 
650 7 |a Glutamate Decarboxylase  |2 NLM 
650 7 |a EC 4.1.1.15  |2 NLM 
650 7 |a Etanercept  |2 NLM 
650 7 |a OP401G7OJC  |2 NLM 
650 7 |a teplizumab  |2 NLM 
650 7 |a S4M959U2IJ  |2 NLM 
700 1 |a Palmer, Jerry P  |e verfasserin  |4 aut 
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