Subthalamic hGAD65 gene therapy and striatum TH gene transfer in a Parkinson's disease rat model

The aim of the present study is to detect a combination method to utilize gene therapy for the treatment of Parkinson's disease (PD). Here, a PD rat model is used for the in vivo gene therapy of a recombinant adeno-associated virus (AAV2) containing a human glutamic acid decarboxylase 65 (rAAV2...

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Veröffentlicht in:Neural plasticity. - 1998. - 2013(2013) vom: 15., Seite 263287
1. Verfasser: Zheng, Deyu (VerfasserIn)
Weitere Verfasser: Jiang, Xiaohua, Zhao, Junpeng, Duan, Deyi, Zhao, Huanying, Xu, Qunyuan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Oxidopamine 8HW4YBZ748 Tyrosine 3-Monooxygenase EC 1.14.16.2 Glutamate Decarboxylase EC 4.1.1.15 glutamate decarboxylase 2