A note on statistical method for genotype calling of high-throughput SNP arrays

We study the genotype calling algorithms for the high-throughput single-nucleotide polymorphism (SNP) arrays. Building upon the novel SNP-RMA preprocessing approach and the state-of-the-art CRLMM approach for genotype calling, we propose a simple modification to better model and combine the informat...

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Publié dans:Journal of applied statistics. - 1991. - 40(2013), 6 vom: 24., Seite 1372-1381
Auteur principal: Yang, Jiaqi (Auteur)
Autres auteurs: Zhang, Wei, Wu, Baolin
Format: Article
Langue:English
Publié: 2013
Accès à la collection:Journal of applied statistics
Sujets:Journal Article SNP arrays empirical Bayes genotype calling algorithm mixture model