Growth Inhibitory Activity of a Bis-benzimidazole-Bridged Arene Ruthenium Metalla-Rectangle and Prism

Two new supramolecular coordination complexes (SCCs), were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, 4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism 6 selectively showed high c...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:	Organometallics. - 1998. - 32(2013), 6 vom: 25. März, Seite 1563-1566
1. Verfasser:	Vajpayee, Vaishali (VerfasserIn)
Weitere Verfasser:	Lee, Sun Mi, Park, Joeng Woo, Dubey, Abhishek, Kim, Hyunuk, Cook, Timothy R, Stang, Peter J, Chi, Ki-Whan
Format:	Aufsatz
Sprache:	English
Veröffentlicht:	2013
Zugriff auf das übergeordnete Werk:	Organometallics
Schlagworte:	Journal Article

Beschreibung
Zusammenfassung:	Two new supramolecular coordination complexes (SCCs), were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor, 4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism 6 selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50 values as low as 8.41 μM for MCF7 cells, as determined from MTS assays
Beschreibung:	Date Revised 21.10.2021 published: Print Citation Status PubMed-not-MEDLINE
ISSN:	0276-7333