Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia

Correlation of single-cell gel electrophoresis and mitomycin C-induced chromosomal breakage for chromosomal instabiligy in children with Fanconi anemia

OBJECTIVE: Fanconi anemia (FA) is characterized by bone marrow failure, congenital abnormalities and predisposition to neoplasia. Hypersensitivity of FA cells to the clastogenic effect of mitomycin C (MMC) provides a unique marker for the diagnosis before the beginning of hematological manifestation...

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Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 51(2013), 2 vom: 24. Feb., Seite 122-5
1. Verfasser: Zhang, Li (VerfasserIn)
Weitere Verfasser: Liu, Qiang, Zou, Yao, Liu, Xiao-ming, Zhang, Jia-yuan, Wang, Shu-chun, Chen, Xiao-juan, Guo, Ye, Yang, Wen-yu, Ruan, Min, Liu, Tian-feng, Liu, Fang, Cai, Xiao-jin, Chen, Yu-mei, Zhu, Xiao-fan
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't Mitomycin 50SG953SK6