Cytochrome P4501A induction in primary cultures of embryonic European starling hepatocytes exposed to TCDD, PeCDF and TCDF

Novel methods that predict the sensitivity of avian embryos to the toxic effects of dioxin-like compounds (DLCs) using either (1) knowledge of the identity of amino acids at key sites within the ligand binding domain of aryl hydrocarbon receptor 1 (AHR1) or (2) a luciferase reporter gene assay that...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 22(2013), 4 vom: 12. Mai, Seite 731-9
1. Verfasser: Farmahin, Reza (VerfasserIn)
Weitere Verfasser: Crump, Doug, Jones, Stephanie P, Mundy, Lukas J, Kennedy, Sean W
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Avian Proteins Benzofurans Polychlorinated Dibenzodioxins RNA, Messenger Receptors, Aryl Hydrocarbon Luciferases EC 1.13.12.- Aryl Hydrocarbon Hydroxylases mehr... EC 1.14.14.1 CYP1A4 protein, Gallus gallus cytochrome P-450 CYP1A5 2,3,4,7,8-pentachlorodibenzofuran U4C2RV3124 2,3,7,8-tetrachlorodibenzofuran XZJ41GQI5D