Silver-zwitterion organic-inorganic nanocomposite with antimicrobial and antiadhesive capabilities

In this work, we demonstrate a convenient, efficient, and environmentally benign strategy to achieving antimicrobial and antiadhesive purposes using a silver-zwitterion nanocomposite. The synthesis of the nanocomposite relies on loading zwitterionic polymer brushes with Ag(+) precursor ions, followe...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 11 vom: 19. März, Seite 3773-9
1. Verfasser: Hu, Rong (VerfasserIn)
Weitere Verfasser: Li, Guozhu, Jiang, Yujiao, Zhang, Yi, Zou, Ji-Jun, Wang, Li, Zhang, Xiangwen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Anti-Infective Agents Polymethacrylic Acids polycarboxybetaine methacrylate Silver 3M4G523W1G Betaine 3SCV180C9W
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245 1 0 |a Silver-zwitterion organic-inorganic nanocomposite with antimicrobial and antiadhesive capabilities 
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520 |a In this work, we demonstrate a convenient, efficient, and environmentally benign strategy to achieving antimicrobial and antiadhesive purposes using a silver-zwitterion nanocomposite. The synthesis of the nanocomposite relies on loading zwitterionic polymer brushes with Ag(+) precursor ions, followed by their in situ reduction to Ag nanoparticle by ultraviolet (UV) irradiation. Both poly(sulfobetaine methacrylate) (pSBMA) and poly(carboxybetaine methacrylate) (pCBMA) have been studied as matrices for the embedding of silver. Well-dispersed silver nanoparticles are embedded into pCBMA matrices. The obtained pCBMA-silver hybrid (CB-Ag) is capable of killing bacteria upon contact and releasing dead bacteria under wet conditions. Results suggest the feasibility of using this nanocomposite system as a robust and reliable antimicrobial and antiadhesive platform for the prevention of microbial colonization 
650 4 |a Journal Article 
650 7 |a Anti-Infective Agents  |2 NLM 
650 7 |a Polymethacrylic Acids  |2 NLM 
650 7 |a polycarboxybetaine methacrylate  |2 NLM 
650 7 |a Silver  |2 NLM 
650 7 |a 3M4G523W1G  |2 NLM 
650 7 |a Betaine  |2 NLM 
650 7 |a 3SCV180C9W  |2 NLM 
700 1 |a Li, Guozhu  |e verfasserin  |4 aut 
700 1 |a Jiang, Yujiao  |e verfasserin  |4 aut 
700 1 |a Zhang, Yi  |e verfasserin  |4 aut 
700 1 |a Zou, Ji-Jun  |e verfasserin  |4 aut 
700 1 |a Wang, Li  |e verfasserin  |4 aut 
700 1 |a Zhang, Xiangwen  |e verfasserin  |4 aut 
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