Synthesis and NMR studies of novel chromone-2-carboxamide derivatives

Synthesis and NMR studies of novel chromone-2-carboxamide derivatives

Copyright © 2013 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 51(2013), 4 vom: 15. Apr., Seite 251-4
1. Verfasser: Gaspar, Alexandra (VerfasserIn)
Weitere Verfasser: Cagide, Fernando, Quezada, Elias, Reis, Joana, Uriarte, Eugenio, Borges, Fernanda
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Letter Research Support, Non-U.S. Gov't Chromones Heterocyclic Compounds
Beschreibung
Zusammenfassung:Copyright © 2013 John Wiley & Sons, Ltd.
Chromones are heterocyclic compounds of natural or synthetic origin that possess relevant pharmacological activities. Versatile functionalization of the chromone nucleus allows attaining of a chemical diversity suitable to perform structure-activity relationships in drug discovery and development programs. Accordingly, the synthesis and identification of novel chromone carboxamide derivatives with electron-donating and electron-withdrawing substituents in different positions of the exocyclic ring are reported in this work. Their complete structural characterization was performed using one-dimensional and two-dimensional resonance techniques. The data acquired are useful for a prompt analysis of related compounds that encompass our integrated medicinal chemistry sketch
Beschreibung:Date Completed 30.01.2014
Date Revised 15.03.2013
published: Print-Electronic
Citation Status MEDLINE
ISSN:1097-458X
DOI:10.1002/mrc.3937