Ionic liquid mediated synthesis and surface modification of multifunctional mesoporous Eu:GdF3 nanoparticles for biomedical applications

A procedure for the synthesis of multifunctional europium(III)-doped gadolinium(III) fluoride (Eu:GdF3) nanoparticles (~85 nm) with quasispherical shape by precipitation at 120 °C from diethylene glycol solutions containing lanthanide chlorides and an ionic liquid (1-Butyl, 2-methylimidazolium tetra...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 10 vom: 12. März, Seite 3411-8
1. Verfasser: Rodriguez-Liviano, Sonia (VerfasserIn)
Weitere Verfasser: Nuñez, Nuria O, Rivera-Fernández, Sara, de la Fuente, Jesus M, Ocaña, Manuel
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Ionic Liquids Europium 444W947O8O Gadolinium AU0V1LM3JT
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520 |a A procedure for the synthesis of multifunctional europium(III)-doped gadolinium(III) fluoride (Eu:GdF3) nanoparticles (~85 nm) with quasispherical shape by precipitation at 120 °C from diethylene glycol solutions containing lanthanide chlorides and an ionic liquid (1-Butyl, 2-methylimidazolium tetrafluoroborate) as fluoride source has been developed. These nanoparticles were polycrystalline and crystallized into a hexagonal structure, which is unusual for GdF3. They were also mesoporous (pore size = 3.5 Å), having a rather high BET surface area (75 m(2) g(-1)). The luminescent and magnetic (relaxivity) properties of the Eu:GdF3 nanoparticles have been also evaluated in order to assess their potentiality as "in vitro" optical biolabels and contrast agent for magnetic resonance imaging. Finally, a procedure for their functionalization with aspartic-dextran polymers is also reported. The functionalized Eu:GdF3 nanoparticles presented negligible toxicity for Vero cells, which make them suitable for biotecnological applications 
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700 1 |a Nuñez, Nuria O  |e verfasserin  |4 aut 
700 1 |a Rivera-Fernández, Sara  |e verfasserin  |4 aut 
700 1 |a de la Fuente, Jesus M  |e verfasserin  |4 aut 
700 1 |a Ocaña, Manuel  |e verfasserin  |4 aut 
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