Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers

Decoupling cell and matrix mechanics in engineered microtissues using magnetically actuated microcantilevers

Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 25(2013), 12 vom: 25. März, Seite 1699-705
1. Verfasser: Zhao, Ruogang (VerfasserIn)
Weitere Verfasser: Boudou, Thomas, Wang, Wei-Gang, Chen, Christopher S, Reich, Daniel H
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Collagen 9007-34-5
Beschreibung
Zusammenfassung:Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A novel bio-magnetomechanical microtissue system is described for magnetic actuation of arrays of 3D microtissues using microcantilevers. This system enables both in situ measurements of fundamental mechanical properties of engineered tissue, such as contractility and stiffness, as well as dynamic stimulation of the microtissues. Using this system, cell and extracellular matrix contributions to the tissue mechanical properties are decoupled for the first time under both static and dynamic loading conditions
Beschreibung:Date Completed 10.09.2013
Date Revised 21.03.2024
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201203585