New practical tools for the implementation and use of ultrafast 2D NMR experiments

New practical tools for the implementation and use of ultrafast 2D NMR experiments

Copyright © 2013 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 51(2013), 3 vom: 28. März, Seite 168-75
1. Verfasser: Pathan, Meerakhan (VerfasserIn)
Weitere Verfasser: Charrier, Benoît, Tea, Illa, Akoka, Serge, Giraudeau, Patrick
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Crotonates Deuterium AR09D82C7G Glucose IY9XDZ35W2 Ibuprofen WK2XYI10QM
Beschreibung
Zusammenfassung:Copyright © 2013 John Wiley & Sons, Ltd.
Ultrafast (UF) 2D NMR is a very promising methodology enabling the acquisition of 2D spectra in a single scan. In the last few years, the analytical performance of UF 2D NMR has been highly increased, consequently maximizing its range of applications. However, its implementation and use by non-specialists are far from being straightforward, because of the specific acquisition and processing procedures and parameters characterizing UF NMR. To make this methodology implementable and applicable by non-specialists, we developed a simple routine capable of translating conventional parameters (spectral widths and transmitter frequencies) into specific UF parameters (gradient and chirp pulse parameters). This macro was subsequently implemented in a Web page, which is available for external users. Although the algorithm was designed for two widely used 2D experiments, COSY and HSQC, it can easily be extended to any other pulse sequence. The robustness of this routine was verified successfully on a variety of small molecules. We believe that this tool will eliminate much of the technical difficulties related to UF 2D NMR and will make the technique accessible to a wider audience of organic and analytical chemists
Beschreibung:Date Completed 20.01.2014
Date Revised 12.02.2013
published: Print-Electronic
Citation Status MEDLINE
ISSN:1097-458X
DOI:10.1002/mrc.3927