3-Hydroxybutyric acid interacts with lipid monolayers at concentrations that impair consciousness

3-Hydroxybutyric acid (also referred to as β-hydroxybutyric acid or BHB), a small molecule metabolite whose concentration is elevated in type I diabetes and diabetic coma, was found to modulate the properties of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) monolayers when added to the subphase...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 6 vom: 12. Feb., Seite 1948-55
1. Verfasser: Hsu, Tienyi T (VerfasserIn)
Weitere Verfasser: Leiske, Danielle L, Rosenfeld, Liat, Sonner, James M, Fuller, Gerald G
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Anesthetics 1,2-Dipalmitoylphosphatidylcholine 2644-64-6 3-Hydroxybutyric Acid TZP1275679