PDMP induces rapid changes in vacuole morphology in Arabidopsis root cells

PDMP (D-L-threo-1-phenyl-2-decanoyl amino-3-morpholino-1-propanol) is a well-known inhibitor of glucosylceramide synthase (GCS), a key enzyme in sphingolipid biosynthesis. Through the resultant increase in ceramides which interact with mTOR and Beclin1 (Atg6), this drug is also known to induce macro...

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Veröffentlicht in:Journal of experimental botany. - 1985. - 64(2013), 2 vom: 17. Jan., Seite 529-40
1. Verfasser: Krüger, Falco (VerfasserIn)
Weitere Verfasser: Krebs, Melanie, Viotti, Corrado, Langhans, Markus, Schumacher, Karin, Robinson, David G
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Ceramides Morpholines RV 538 73257-80-4 Calcium SY7Q814VUP