Analysis of the prognosis and clinical factors in primary vesicoureteral reflux patients

OBJECTIVE: To analyze the relationship between the prognosis and clinical factors of primary vesicoureteral reflux (VUR) patients under the condition of non-surgical treatment

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 50(2012), 8 vom: 16. Aug., Seite 587-92
1. Verfasser: Xu, Jing (VerfasserIn)
Weitere Verfasser: Xu, Hong, Zhou, Li-jun, Shen, Qian, Sun, Li, Bi, Yun-li, Wang, Xiang
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Anti-Bacterial Agents
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245 1 0 |a Analysis of the prognosis and clinical factors in primary vesicoureteral reflux patients 
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520 |a OBJECTIVE: To analyze the relationship between the prognosis and clinical factors of primary vesicoureteral reflux (VUR) patients under the condition of non-surgical treatment 
520 |a METHOD: The medical records of the patients who were diagnosed as VUR by micturating cystourethrography (MCU) from January 2000 to December 2009 in Children's Hospital of Fudan University underwent non-surgical treatment, and followed up for more than one year then had repeated MCU, were retrospectively reviewed 
520 |a RESULT: A total of 73 children (30 boys, 43 girls) were included in this study. The percentage of mild reflux (grade I-II) was 19.2% (14/73), that of moderate reflux (grade III) was 53.4% (39/73), and that of severe reflux (grade IV-V) was 27.4% (20/73). Among 73 patients, 27 (37.0%) patients were found to have renal damage. The average interval of repeated MCU was (1.29 ± 0.40) years (1 - 2 years). After follow-up, it was found that the reflux grade was relieved in 41 (56.2%) patients, of whom 27 (37.0%) patients achieved complete resolution, 32 (43.8%) patients did not have remission in reflux grade, of whom 13 (17.8%) patients had worsened reflux grade. Logistic regression analysis showed that VUR patients with renal damage at initial diagnosis was an important clinical factor to affect reflux remission (P = 0.000), complete resolving (P = 0.008) and result in worsening (P = 0.002) 
520 |a CONCLUSION: A certain proportion of primary VUR patients could get reflux grade self-resolution, it was also quite common in severe VUR patients. VUR patients with renal damage at initial diagnosis was an important clinical factor affecting the reflux grade prognosis. Mild and moderate VUR patients with renal damage were at risk of worsening. VUR patients with high reflux grade had normal renal status could still get remission or even disappearance of VUR. But severe VUR patients with renal damage were still recommended to receive surgical therapy 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 7 |a Anti-Bacterial Agents  |2 NLM 
700 1 |a Xu, Hong  |e verfasserin  |4 aut 
700 1 |a Zhou, Li-jun  |e verfasserin  |4 aut 
700 1 |a Shen, Qian  |e verfasserin  |4 aut 
700 1 |a Sun, Li  |e verfasserin  |4 aut 
700 1 |a Bi, Yun-li  |e verfasserin  |4 aut 
700 1 |a Wang, Xiang  |e verfasserin  |4 aut 
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