Mechanistic insights into the stabilization of srcSH3 by PEGylation

Protein PEGylation (attaching PEG chains to proteins) has been widely used in pharmaceuticals and nanotechnology. Although it is widely known that PEGylation can increase the thermodynamic stability of proteins, the underlying mechanism remains elusive. In this Article, we studied the effect of PEGy...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 28(2012), 46 vom: 20. Nov., Seite 16133-40
1. Verfasser: Meng, Wei (VerfasserIn)
Weitere Verfasser: Guo, Xinlu, Qin, Meng, Pan, Hai, Cao, Yi, Wang, Wei
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Polyethylene Glycols 3WJQ0SDW1A src-Family Kinases EC 2.7.10.2