Long-term disease stabilization by Strontium 89 (89Sr) for castration and docetaxel-resistant prostate cancer : a case report

A 67-year old man was diagnosed with advanced prostate cancer with multiple pelvic lymph nodes and multiple bone metastases (cT2N1M1b), with an initial prostate specific antigen of 1,300 ng/ml. Prostate biopsy specimens revealed poorly differentiated adenocarcinoma, Gleason's score 5+3. He was...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 58(2012), 9 vom: 06. Sept., Seite 515-8
1. Verfasser: Kamiyama, Yuki (VerfasserIn)
Weitere Verfasser: Iguchi, Ryo, Makino, Yuki, Kanamaru, Sojun, Ito, Noriyuki, Imanaka, Kazufumi
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 2012
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports Journal Article Strontium Radioisotopes Taxoids Docetaxel 15H5577CQD
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520 |a A 67-year old man was diagnosed with advanced prostate cancer with multiple pelvic lymph nodes and multiple bone metastases (cT2N1M1b), with an initial prostate specific antigen of 1,300 ng/ml. Prostate biopsy specimens revealed poorly differentiated adenocarcinoma, Gleason's score 5+3. He was treated with maximal androgen blockade (MAB) from 2001, but showed resistance to hormone therapy and docetaxel in 2007. External radiation therapy for bone pain was difficult due to multiple lesions. 89Sr therapy was started in 2009. The therapy could be performed 5 times without any side effects. Good pain control and decreasing PSA was obtained at each dose 
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