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01000caa a22002652 4500 |
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DE-627 |
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20250214121323.0 |
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231224s2012 xx ||||| 00| ||chi c |
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|a pubmed25n0738.xml
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|a (DE-627)NLM221604499
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|a (NLM)23040773
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a chi
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1 |
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|a Leng, Yu-xin
|e verfasserin
|4 aut
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|a Effect of 45 degree angle semirecumbent position on ventilator-associated pneumonia in mechanical ventilated patients
|b a meta-analysis
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|c 2012
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 01.08.2013
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|a Date Revised 08.10.2012
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To systemically analyze the effect of 45 degree angle semirecumbent position on the incidence of ventilator-associated pneumonia (VAP) and other outcomes in mechanical ventilated patients, and to evaluate whether 45 degree angle semirecumbent position is superior to 25 degree angle-30 degree angle head of bed (HOB)
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|a METHODS: The randomized controlled trials (RCTs) comparing the effect of different HOB on the outcomes of mechanical ventilated patients were searched (from 1st January 1990 to 20th July 2012) from five databases including the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, China Knowledge Resource Integrated Database (CNKI), and Wanfang Database. Meta analysis was conducted using RevMan 5.0 software
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|a RESULTS: Data extracted from five RCTs with a total of 427 patients were analyzed. The risks of developing clinically diagnosed VAP were significantly lower among the patients in semirecumbent 45 degree angle position compared to the patients in lower position [15.96% (34/213) vs. 26.64% (57/214), relative risk (RR)=0.57, 95% confidence interval (95%CI) 0.39 to 0.83, P=0.003], while no significant differences were detected between the two groups regarding the mortality rate [27.04% (53/196) vs. 28.22% (57/202), RR=0.93, 95%CI 0.68 to 1.27, P=0.66], the length of intensive care unit (ICU) stay [weighted mean difference (WMD)=-0.45, 95%CI -1.08 to 0.18, P=0.16] and the percentage of antibiotics treatment [71.11% (32/45) vs. 60.87% (28/46), RR=1.14, 95%CI 0.85 to 1.53, P=0.37]. Two of the five trials (91 patients) were included in the sub-analysis between 45 degree angle group (45 patients) and 25 degree angle-30 degree angle group (46 patients). The results showed that comparing with 25 degree angle-30 degree angle, 45 degree angle semirecumbent position had no significance in improving patients' clinical outcomes
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|a CONCLUSION: This study proved that the clinically preferred semirecumbent 45 degree angle position did have effect in reducing the incidence of VAP, nevertheless, whether it's superior to 25 degree angle-30 degree angle needs to be confirmed by larger-scale, higher-quality RCTs
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|a English Abstract
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|a Journal Article
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|a Meta-Analysis
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|a Research Support, U.S. Gov't, Non-P.H.S.
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| 700 |
1 |
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|a Song, Ya-han
|e verfasserin
|4 aut
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|a Yao, Zhi-yuan
|e verfasserin
|4 aut
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| 700 |
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|a Zhu, Xi
|e verfasserin
|4 aut
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| 773 |
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8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 24(2012), 10 vom: 31. Okt., Seite 587-91
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
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|g volume:24
|g year:2012
|g number:10
|g day:31
|g month:10
|g pages:587-91
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|a GBV_USEFLAG_A
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|a SYSFLAG_A
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|a GBV_NLM
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|a GBV_ILN_350
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|a AR
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| 952 |
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|d 24
|j 2012
|e 10
|b 31
|c 10
|h 587-91
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